Dec 23rd 2016 by Charactur • 12 Questions • 4717 Points
My short bio: Hey Reddit! My name is Anthony van der Meer and I am the 23 years old director of Find my Phone. After the film went viral on Youtube, I saw a lot of questions. So now I am here to answer them. Feel free to ask about the legal, technical, ethical or cinematic aspects of the film.
What do you like most about playing games, and what would you like to see more of in games?
Hey, I'm 8 months clean off of heroin, living in Seattle. Have there been any long term studies into the effect of using marijuana during cravings? That's what I've been doing - smoke a big bowl and sleep through it til tomorrow. But am I actually just putting off an inevitable relapse without learning better coping mechanisms?
Edit: Holy wow! I was not expecting such a response from my little throwaway comment. I am totally overwhelmed by this show of support and I'm going to send the day getting to everyone. Thank you!
Will you do a second movie if the phone goes back online again?
i like the competitive spirit people have when playing multiplayer games. I would like games of the mmo genre to work on guilds and community's staying together long because now a days guilds break up/become inactive way to fast
Oh my god, thank you THANK YOU THANK YOU for sharing your story. There are absolutely ZERO long term studies about this, but I hope to be the author of those one day!!! Based on the literature, the only things that could definitely enhance your recovery are social support (being meaningfully connected with humans around you) and mindfulness meditation. YOU CAN DO IT.
Great question! Easy sells for us are definitely fresh seasonal fruit like citrus, kiwis, and persimmons. We also see a lot of demand for healthy greens like kale, broccoli, and lettuces, which are normally expensive in stores so people love the savings plus the convenience of having it delivered. Hard sells are anything with visible scarring, which can look weird at first, but once you peel or chop the item you realize that it's the same as what you could have gotten in the stores. To be honest though, one of the most common responses we get from people when they first get their box is "this isn't ugly at all!" It is astounding how strict the cosmetic standards at grocery store standards have become over the years.
Yes, check the last 15 seconds of the film ;)
My understanding is that "ugly" produce is what is sold to companies that turn them into juices, Broth, and pieces so small that the defects are mitigated (such as baby carrots).
Is this the case? If so, how much waste is there if you account for these products?
When? We need Find My Phone: Roamin' in Romania ASAP.
You're right -- a lot of ugly veggies have a processor market. Apples, oranges, and other fruit tend to. Often even when there is a processor market, farmers are forced to sell it below cost. So we buy some of that stuff and are able to pay a lot more than processors do. But most items -- basically all the field packed product like celery, broccoli, cauliflower, etc. don't have a processor market and would be left in the field. And then even items like kiwis, eggplants or any other pears besides the bartlett often go to animal feed for 1 cent per pound.
Love the title. It's hard to tell. I will focus the sequel on the complete life cycle of the phone.
A prequel about where my iPhone ended up will probably be released before that. I am in the pre-production of that film now and I am planning on releasing it next year. It all depends on the developments of the story
Hi Ben! As an Imperfect customer, I first want to say thank you for introducing me to world of crazy fruits and vegetables! I've tried lots of different produce that I normally would never have eaten, and I'm curious -- what is the most "exotic" fruit or vegetable you've ever eaten, and how did you prepare it?
What are the unexpected/interesting results of your film going viral?
Thanks for the support! So happy to hear you're loving it. I cooked lotus root once which is basically this big gnarly root that grows in the muck. You slice it up and it looks like swiss cheese in the middle. Like a big mud tuber. It's really delicious and crispy fried tho. https://www.google.com/search?q=lotus+root&rlz=1C1CHBF_enUS723US723&source=lnms&tbm=isch&sa=X&ved=0ahUKEwizoO6EhYvRAhXJLmMKHTBcAZAQ_AUICCgB&biw=1920&bih=974
I wasn't expecting the film to go viral. So that was actually unexpected for me.
Any plans on ever expanding into East Coast? Live in CT and have been waiting to be able to get some beautiful ugly produce for a while!
What's the first thing to consider when doing a film. Is it story? Characters? Scenes?
Totally! We hope to be on the East Coast by 2019. Feel free to pre-sign up on our website to get an email when we launch. imperfectproduce.com
I always start with a story idea. I always try to minimize the characters and make a draft were I just summarize the crucial scenes to tell the story. I think that's a good way to start.
The Moba communities also often have many young hormone-filled teens who will use slurs and really just plain old mean language without realizing who they may be hurting directly.
Wow. Love how unbiased those grants are. Do you feel this also has an impact in the how published peer-reviewed results are framed?
ya i get called stuff all the time and i play support/jungle
I would like to think not. Data is data. You can spin it however you like in your discussion, but data doesn't lie. It just is. Regardless of an investigator's hypothesis, bias, or funding agency... ball don't lie.
Has anyone ever told you, you look like Anthony Kiedis from Red Hit Chili Peppers? Because you do, if not than now you have.
Many of my fellow physicians use urine drug screens as part of pain contracts with patients receiving opioid narcotics. They will refuse to prescribe narcotic medications if patients test positive for any illegal drugs, marijuana included. I've always found this odd because they rarely screen for alcohol use, nor do they refuse narcotics to patients who use alcohol.
My question is, what are the effects of marijuana on opioids from a patient safety perspective? Does marijuana interfere with the metabolism of opioids?
From a safety perspective, all signs point to cannabis LOWERING the opioid risk. When patients have access to cannabis, they self-taper their opioid intake by roughly half. In states with medicinal cannabis laws, there is a 25% drop in opioid overdose deaths.
In terms of basic pharmacology, cannabinoids and opioids interact synergistically to produce pain relief (the two together provide much greater relief than they do alone). However, this does not appear to be true for the side effects like sedation and motor coordination (cannabis enhances the good effects of opioids, but not the bad effects). EDIT: A lot of this work was done in animals.
We don't have any evidence of cannabis interfering with opioid metabolism. The precise mechanisms of the drugs' interactions are poorly understood, and the topic of my ongoing research!
Do you record at all? Any videos we could see? Also, do you primarily play off of systems or PC?
Is there any evidence that cannabis increases the half-life of opioids? Or that it can worsen the most severe side effects such as respiratory depression?
twitch.tv/tehzuh and i play pc mostly but i can play consoles with the mouse/keyboard device .
No, in fact there is evidence to the contrary. The timecourse of opioids is unaffected by cannabinoid administration. Opioids induce respiratory depression, whereas cannabinoids induce tachycardia (increased heart rate). I actually answered this very question at my Ph.D. thesis defense! Edit: to be concise.
I am a person who uses both opioids and cannabis for chronic pain, if you have any questions fire away.
/u/CourageousKoala keep an eye on your inbox!
Have you been offended by how strangers react to you in public? If so, can you give the most often example?
Hello. I was a homeless alcoholic by 19. I managed to weasel into the military, where my alcoholism was accelerated to comical levels. Just, hilarious. Upon separation, I took up smoking pot to try and replace the alcohol with something else. It worked.
Marijuana quite literally saved my life. I now hold multiple degrees and have a very nice University desk job. If anyone ever says it's just replacing one addiction with another, they're right. But only one has negative consequences. The other has been an unimaginable boon to the successes I've had over the past decade.
I've had two board certified, well respected pain doctors recommended it (in certain words, and with the caveats they can't and won't prescribe it, etc etc) to me over my alternative pain regimen: Norco. I'm totally off opiates now, something I never thought possible and don't have to go through grueling monthly withdrawals anymore, since I started using cannabis. It's been a godsend, and I was devastated to move from CA to TX.
Oh, you think I haven't been lurking there for like, ever? But yes, I will take you up on your offer to participate in scientific research. My compensation for your contribution will be witty quips and gracious thanks.
Thanks for the kind words. You're very welcome for the reminder. We get our produce from dozens of farms all over the West coast. Most of our produce comes from California simply because this is where most of our country's produce is grown and this is where most of the potential for waste is. We source seasonally available ugly produce so sometimes we do buy produce from other areas like Arizona, Washington, and Mexico. In terms of tradeoffs we love to source from local farms whenever possible for the obvious ecological and environmental reasons. That said, food waste is a problem that is bigger than just California and in order to properly serve our customers year round we will divert "ugly" produce from further afield when necessary.
Thanks for your answer, I have a hypothesis that cannabis reduces ethanol craving, this is great!
A lot of grocery stores look at their produce section as a primary way to keep a strong reputation for quality and to get customers in the door. I've talked to and worked with grocery stores and they basically just don't think people would buy this. The other reason is they fear ugly produce sales could take up precious square feet while cannibalizing sales for their premium product. However, Imperfect has worked with a couple grocery stores and mainly saw data pointing to an overall increase in sales. Now, a year or two after Imperfect's launch we're starting to see a few grocery stores develop pilots.
My wife and I frequent a farm locally where we pick our own produce. I love this idea, and bringing awareness to people that there is perfectly good food to eat, that just may look different then you are used to.
I have been mostly unemployed for 8 months, surviving off web/contract work. I love the idea of promoting this way of thinking. I also live in the LA area, so this is exciting. Which leads me to my question: What would it take for me to get a job working for you and your company? (I have a resume I can send).
ya ill be on tomorrow 2
Yeah, logistics is one of the hardest parts. In terms of getting the produce to us, we pay trucking companies a fee per pallet to go to our farms, pick up the produce and bring it to our warehouse on a refrigerated truck. We use a local startup called AxleHire to do the last mile delivery to customers' doorsteps.
Holy crap you're styling on people only using your mouth for a control? That's crazy. There is zero way I would make it out of bronze like that. Keep it up, overwatch is a fantastic game.
Cannabis kills my craving for food(can make me hungry sometimes) and alcohol. How do you feel about teenage use of cannabis? or teenage use of non-psychoactive cannabis extracts such as CBD?
TL;DR: Don't mess with your developing brain, unless you absolutely have to because of medical reasons (intractable epilepsy etc).
Research has clearly shown that consistent adolescent use of cannabis (under 21 yrs of age) is strongly associated with cognitive deficits as an adult. The human brain does not finish developing until approximately 21 years of age, and intervening with its normal development is usually not worth the short-term benefits of cannabis.
If you or your child are considering medicinal cannabis for your condition, you should have lengthy discussions with your doctor about short vs. long term effects of cannabis. This includes CBD, which we don't fully understand.
As of now we deliver to the Bay Area, and are expanding to the LA area in the beginning of 2017! Feel free to pre-sign up on our website to get an email when we expand to your area. imperfectproduce.com !
What do you mean specifically by cognitive deficits?
Retention of information. Reaction time. Learning new tasks and the like.
Hey friends! Thanks again for the wonderfully thoughtful questions. This was so much fun. I have to run now but would absolutely love to do a follow up session some time. Happy holidays!
I'm really impressed that you can play league!! Who do you main as and where??
Holy crap you guys, have you seen the comments on imgur? That place is the sewer of the internet.
It's all GMO free! And about 1/2 the produce we sell is conventional and the other 1/2 is organic.
Is there anything game developers can do to better support people in yours and other similar conditions? I'd imagine there's plenty of situations where there's an obvious and easy solution but developers just don't think about it. Any insight?
If that's your bar for "sewer of the internet", do yourself a favor and keep that bubble unburst.
Also: Thank you so much for everything you do to improve the accuracy of our public knowledge and perception of cannabis. Over the last year or so, I've really had my eyes opened to what that drug actually is. It's so strange to me now to think about how many people hold completely unfounded beliefs regarding that plant, and I really respect people like you for doing everything you can to see how far this medical goldmine goes.
besides making more game that let you rebind the mouse buttons not really or at least i cant think of any.
- HA! Bubble shall remain intact, thank you kind bagelmeister!
- Thank YOU for being open minded and allowing knowledge to trump stigma! It's only by "coming out on cannabis" that we can truly begin to have progress on this issue!
How long did it take to get used to playing with a mouth stick? Do you control your wheel chair with a mouth stick as well?
I use CBD oil to reduce inflammation from my JRA (didn't feel so juvenile before the CBD) and I feel so liberated! I can make a complete fist again and I feel like I have my 25 y/o body back! When I heard that CBD is going to be Schedule 1 I was devastated and wanted to kick a lead ingot. Reading about the side effects caused by "real" RA meds scare me half to death and I'm nowhere near desperate enough to take them. Why is it that the DEA like to keep barbed sticks up their asses?
When i first started using it my neck would get sore but now im fine. i use the back of my hand for my wheel chair
Dang, what I wouldn't give to know why the DEA insists upon this wretched self-sodomy. I too, was devastated by their recent decision, which, fortunately, seems to be totally illegal and a gross over-stepping of their duties. We'll see what happens there. I'm SO happy to hear that you've found a way to get some relief. I have a close friend with JRA, I truly know your pain, I've had hour upon hour of conversation about this. Thanks for sharing!
What exactly does "how cannabis interacts with opioids" mean? From a physiological POV?
Having been a heavy pot smoker most of my life.. and having a few years where I was an opiate addict, I've mixed the two more than I'd care to admit..
Yes, from a physiological standpoint.
In my career, I have studied the acute effects of combined cannabinoid/opioid administration (for pain relief). I have also looked at how chronic cannabinoid exposure effects opioid pain relief, and opioid tolerance (the loss of effectiveness with repeated use). I have also studied how chronic opioid exposure effects cannabinoid pain relief.
My ongoing and future studies are to examine the cellular and molecular mechanisms behind enhanced pain relief and reduced opioid tolerance, as well as the addictive potential (or lack there of) of combined opioid/cannabinoid administration.
I'm in a wheelchair with a degenerative neurological condition so my upper limbs will go one day. Will I still enjoy dota? (it's similar to LoL if you don't already know) do you think I'll be able to maintain my ranking? How much learning goes into what you do?
Considering the attention given to THC, how much of your research focuses on cannabidiol? Has it been shown to be more or less useful than the psychoactive cannabinoids for things like pain management?
o man i can at least use my arms so i couldn't tell you. how i play is i re bind my left click and right to my keyboard and i rest my hand(that doesn't work btw) on a track ball mouse.
CBD does not seem to provide as much pain relief as THC or other CB1 receptor agonists. The reason is that CBD does not directly activate the CB1 receptor. My work and others has shown that CB1 activation in the part of your brain that is the headquarters for pain control (the periaqueductal gray) shuts off pain for the whole body. CBD seems to have some anti-inflammatory effects, probably mediated by the immune system, so this may be a different mechanism for pain relief. My personal research does not involve CBD, but I follow this VERY closely!
Have you tried stardew valley? do you think the controls can be adjusted for your playstyle? It just got ported to the XBOne. I'd love for you to be able to play it.
Wow, good for you! You are a true inspiration.
My mother and I argue constantly about the uses of marijuana and she claims that "even if it could cure cancer", she would be against it (which I HIGHly doubt). What are some solid researches/studies I could show her to prove that it is more than just a recreational habit, and some to prove that marijuana in fact does not kill all of our brain cells?
Unfortunately, overcoming stigma like this is going to be a generation-long process. In my experience, this stigma is harder to overcome by showing someone solid data, and the shift really happens when there is an emotional appeal. Lots of videos on Youtube of kids' seizures stopping after an oral tincture, or parkinson's patients having normal conversations after a j. If you REALLY want a list of solid studies, there are literally thousands of them, too many to link here!
I'm about 6 months clean from a crippling opioid addiction. I've used, and continue to use, kratom in my battle. I still smoke cannabis from time to time, but only in very small amounts. I've had more than one cannabis-induced panic attack since quitting opioids. My anxiety is still severe, even after 6 months. Have you done any research on kratom (Mitragyna Speciosa)?
I've found that the two go very nicely with each other. Since kratom doesn't cause respiratory depression, much like cannabis, there's no real danger in ODing. Kratom has literally saved my life, and if you haven't done any research on it, I would strongly recommend that you do. For me, it also does a better job than cannabis at attenuating alcohol consumption.
I'd be more than willing to answer any questions you may have to the best of my ability. Thank you for doing this AMA!
its a metal stick that has a piece of plastic on the end. Its fairly simple really.
Thanks for the guidance, I think you're really onto something, I will definitely look into this! As far as the anxiety goes, the side effects that cannabis can have on cardiac activity could definitely contribute to that: your mood and your heart rate are very closely related. That's why beta blockers are so good as anti-anxiety meds: they directly reduce heart rate and "trick" your brain into thinking everything is chill.
How would you make the process of playing easier?/what are some problems you have while playing? Im a studying User Experience (UX) and would love to work on something like this
Thank you for you work, first and foremost. I use cannabis for pain management. I was injured in the military and have chronic low back pain, for which I was prescribed many things, starting with ibuprofen 200mg-800mg, Lortab, Vicodin, and Methadone, among others. The side effects of the prescription meds were awful, such as bleeding ulcers, constipation, hemorrhoids, cramping, etc.
I tried cannabis for the first time at age 31, and it has been a life-saver. I don't understand why, but the cannabis does not exactly eliminate the pain, but rather causes me to not really be concerned with it. Can you explain why/how (aside from the high feeling) that cannabis has this effect on pain?
if more games had auto walk that would make things SOOOOO much easier. Also if more fps games let you rebind the mouse keys.
First of all, thank you for your service and sacrifice. What you are describing, in terms of your ability to cope with pain, is the same thing that we observe with cognitive behavioral therapy and mindfulness meditation for pain. I can't, based on data, explain why this phenomenon occurs, but I think what you are describing has serious clinical usefulness!
I know the question is strange but how do you put on your headphones ?
Damm I wasn't aware it was that significant. That sounds super promising! I really interested in what future research will bring.
I'd love some articles! I'm not involved in any medical/neuroscientific studies or research, I'm just a philosophy student who find neuroscience really fascinating. That said, I'll read whatever you'll recommend!
A colleague in my department used to do clinical pain research in Isreal, where cannabis medicine is booming: https://www.ncbi.nlm.nih.gov/pubmed/?term=haroutounian+cannabis
Same result, this time out of Harvard: https://www.ncbi.nlm.nih.gov/pubmed/27790138
Do the doctors have a timeline for stem cell integration or is it a mystery? Like... Sweden or somewhere has to be doing stem cell injections. Right?
Hi, I'm a 45yr old male stuck in a wheelchair, I have C.M.T. and E.D.S. and I suffer from lots of chronic pain, plus depression. For pain I take 2 Tylenol 3s 4 times daily and 1MG of Nabilone twice daily. I don't think my doctor really approves of either, I had to fight a bit to get anything. I don't smoke pot or drink alcohol. I don't think these meds are working very well any more. Do you know of any other options? Or is that it for me?
From hat i keep hearing its soon but i cant do any out of state treatments our else i cant do any of the usa ones.
Honestly, it sounds like you need a more compassionate doctor. You need someone who is supportive of your health and your personal goals. That's where I'd start if I were in your wheels. Best of luck <3
You are pretty amazing... from where do you take the strength?
Do you use cannabis yourself?
I currently live in the state of Missouri, which does not yet have any legal uses for cannabis. In other legal contexts/states, when I did not have anything at stake (for instance, a DEA license for conducting research), I was known to partake. It would be a bit hypocritical for me to lack a first-person perspective!
I think missouri will be one of the last states to make weed legal.
FPS games are super hard for me. I play h1z1 atm and its hard for me to aim and shoot and strife back n fourth at the same time.
Not if I have anything to do with it! I was just at the state capitol yesterday, meeting with Republican law makers on the verbiage for the new medical cannabis bill. Headed back in a few weeks once the new legislative session is underway.
You're a good looking dude! Do you have a girlfriend/wife? How do/did you navigate the dating scene with your situation?
Does recreational use ever become physically harmful at a point? Basically, how often is too often?
i had a gf when i got hurt and we stayed together for like 2more years after that. Dating scene lol. i dont try n date anyone because atm i like doing the stuff i want to do.
I'll refer you to the DSM-5 for the criteria on cannabis use disorder. If those items start to creep into your life (and granted, I'm no recovery professional) it's probably time to chill. Yes, cannabis can definitely become harmful, but probably not in the way you're thinking: more likely in the psycho-social realm than the biological health/longevity realm. Edit: disclaimer.
Could you shed a bit more light on what you mouth stick is? I'm curios to see how you would his it to play games
BTW glad to see something so horrible wouldn't keep you from gaming
I recently had knee surgery done and was prescribed Norco for pain. I felt side effects from it that may have been purely in my brain (fever dreams, lethargy, and a few other things), so I stopped using it. My knee still aches during the day and it's still difficult to get a good nights sleep. Since marijuana is pretty much legal here in California now, I was thinking about it as an alternative to popping Advil all the time. My question is this: Aside from trial and error, is there a way to find the right amount and the right type of marijuana to help with the pain and/or help me sleep at night?
its just a long metal stick that i can adjust in size that i hold in my mouth to press buttons on my keyboard. Imagine a long finger but in your mouth.
aaaaaaaaaaahhhhhhhh! I wish there was a better way than trial and error! This is my life's mission, you shouldn't have to be your own guinea pig, health care professionals SHOULD be able to answer this question for you! Edit: to be concise
What do you think about Pharmaceutical corperations in general? They hold alot of lobbying power in government. And seem to only care about profits rather than opioid addiction (big problem here in Portland OR metro area).
Bonus question what's the percentage of success if someone with a GED asked someone with a PhD out on a date? (this is a purely hypothetical question by the way, just random)
some lady comes to my house 1once a year n sometimes brings them . if she doesn't i have to buy them for a $100 each...i only have one atm
We need big pharma, they are a necessary evil. There are a lot of VERY effective, life-saving medicines out there that would not exist if it weren't for them. I agree that their motives are not always the best, but one of the great things about cannabis is it's existence in the public, rather than patented sphere. If they want to develop more cannabis-based medicines, I say bring it on! WE NEED HALP. Bonus answer: hypothetically, if the PhD had a spouse, as evidenced by AMA proof (wedding ring) then the statistical probability of a date would be around 0.001%.
How are you typing? And howlong does it take to type sentences? Does your speed improve over time?
im using the mouth stick and it takes as long as using 1 finger i think lol
Dang! You beat me to it!
any interest or previous experience with psylocin and its serotoninergic properties? opinions on ssris, snris, or maois?
super mario? i like it but the wii is super hard for me to play.
I can say that CBD is a partial agonist at one of the serotonin receptors. Probably not the answer that you're looking for, but that's about all I got!
Do you live pretty comfortable with your PhD in neuroscience? I have gave some thought about going into virology/immunology/neuroscience/biochemistry and would like to know about your life. Financially, socially, work-wise, what are the good and bad things that comes along with being a scientist?
I can only speak about academic neuroscience research (working within the University system), which is incredibly rewarding… and frustrating, and difficult.
The biggest thing you need in order to succeed is a proactive approach to your education/career. I have found that the most successful people treat their science as their own small business: you are in charge of your own success, no one is going to remind you when your deadlines are, or push you as much as you need to push yourself. Some people don’t do well under these circumstances.
Graduate school consists of many, many long days of straining your brain. There are a lot of sacrifices: you might miss your own birthday because you’re in the middle of an experiment (true story).
As a post-doc, you will still be working hard, and all of your friends who don’t work in science will probably make way more money than you. The payoff is huge though: you don’t punch a time clock. You get to decide what you work on, and you often come to work without feeling like it’s actually work: you just enjoy it. The schedule is flexible, and you get to travel a lot to present your work at conferences (if you/your boss has money anyway… money is always an issue).
These things are also true when you become a P.I. (Principle Investigator/professor). At this point you somewhat become a slave to the NIH, and the stress of writing grants and maintaining funding (so you don’t have to fire everyone when you run out of money) is pretty intense.
At some point in this process, a lot of people realize that the stress is not worth the autonomy, and they choose a different path: there are a lot of careers out there that you can use a neuro PhD for, without having to constantly write grants and deal with the super slow/frustrating academic bureaucracy.
If you pour a TON of effort and practice into the thing that you are both good at, and interested in, you are very likely to be happy. Good luck.
Ya i went to Shriners hospital for a while and the one was sent home for about a year.
no but its a great idea and would work super easy.
How do you go about building games and which ones are your favorite to work on?
by building games i meant games like minecraft and terraria but i usually just build whatever in them.
i do not own it but it looks cool.
Could you please elaborate on the very start of your gaming journey following your accident? I'm wondering if there was a day where you decided to barrel through frustrations and commit to learning the new process, even if it was very intimidating, and would love to hear about that.
When i got hurt i started playing star wars galaxies alot. The only fustrations i had where getting the set up right because i went to shriners hospital for kids and they helped me alot there
Would you rather; regain the use of one arm, or both legs?
both legs because i can move my arms i cannot move my wrists/hands
So how do you use your joystick, if you know what I mean? Does it still work?
lul i dont use it as i dont have a gf and my hands dont work
its normal lol but my neck is pretty muscular when im not falling over
Not related to gaming, but Im curious how you became quadriplegic? :)
a hit and run car accident.
i have never played any ff game but does kingdomhearts count?
its not full the mouth party is pretty thin.